胎儿颈项透明层厚度检测在预测胎儿畸形中的应用价值

The Value of Nuchal Translucency Thickness Measurement in the Prediction of Fetal Malformation

目的探讨胎儿颈项透明层厚度值对于胎儿畸形的预测意义。方法选取2015年5月至2016年5月在我院检查的孕11~13^(+6)周单胎妊娠妇女共421例,随机分为实验组183例及对照组238例,实验组行经腹联合经阴道超声检查;对照组只行经腹超声检查。观察胎儿解剖结构,检测颈部透明层厚度及胎儿头臀径长度,随访观察孕妇及胎儿情况。结果在受检的421例孕妇中,随访及中孕期筛查中有45例为胎儿畸形,其中有36例NT值大于临界值。经腹超声检查与联合经腹及经阴道超声检查相比,NT测量值无明显统计学差异(P>0.05)。结论早孕期采用彩色多普勒超声检查颈部透明层厚度对于胎儿畸形的预测有积极的意义,采用NT>2.5 mm更有应用价值,且不同的超声检查手段对于NT值的检查没有显著的差别。

Objective To explore the meaning of prediction of fetal nuchal translucency thickness to fetal malformation. Methods Selecting the pregnant women with the early gestation between 11 and 14 weeks who took ultrasonic examinations in our hospital during the years in May 2015 to May 2016, we randomly divided them into two groups, one of which took the transabdom- inal sonography containing 238 pregnancy women while the other group underwent the transvaginal sonography. The fetal anatomical structures were observed and the NT thickness and the crown-rump length were measured. We follow up the conditions of the ob- jectives. Results Of the 421 pregnancy women, 45 were identified the fetal malformation. When compare the transabdominal alone and the unity of the transabdominal and the transvaginal uhrasonography, there are no significant differences between two groups. Conclusion There are positive meaning of the examination of NT thickness by ultrasound and the cut-off level can be 2.5mm. Whatmore, the different methods for measuring is no significantly different.