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宁德地区HPV联合TCT检测在宫颈癌前病变及宫颈癌筛查中的价值研究 被引量:6

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摘要 目的探讨人乳头瘤病毒(HPV)联合液基薄层细胞制片术(TCT)在宫颈癌前病变及宫颈癌筛查中的价值。方法已筛查过HPV及TCT的患者6731例,对其结果进行回顾性研究。结果 HPV感染843例,其中高危型感染353例;TCT阳性420例,阴道镜检查为炎症138例(其中HPV阳性20例),≥宫颈上皮内瘤变(CIN)Ⅰ282例;HPV阳性并且TCT阳性302例;230例CINⅠ患者中,HPV敏感度95.65%,TCT检出敏感度80.00%。80例CINⅡ患者中,HPV敏感度98.75%,TCT检出敏感度97.50%。16例CINⅢ患者中,HPV敏感度100.00%,TCT检出敏感度93.75%。5例宫颈癌患者中,HPV敏感度100.00%,TCT检出敏感度100.00%。结论 HPV联合TCT检测有助于提高宫颈癌前病变及宫颈癌筛查的敏感性及特异性,有助于细胞学异常的分流管理。HPV和TCT联合检测对宫颈癌前病变与宫颈癌的初筛有积极作用,尤其适合于宫颈癌的早期诊断,值得临床大力推广。
机构地区 宁德市中医院
出处 《中国实用医药》 2016年第3期101-102,共2页 China Practical Medicine
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