共同性斜视患者眼表泪液情况研究

Analysis of ocular surface condition in patients with concomitant strabismus disease

目的利用Oculus眼前节分析仪研究水平斜视患者眼表泪液情况。方法用Oculus眼前节分析仪研究西安市第一医院眼科门诊诊断为水平共同性斜视（82例外斜视及67例内斜视患者）的眼表情况：包括泪河高度、刺激性泪河高度、眼红指数、非侵袭性BUT、平均BUT等。结果外斜视患者泪河高度为（0．21±0．06）mm，内斜视泪河高度为（0．17±0．05）mm，两种类型斜视患者第一次BUT〈6s，平均BUT〈7s，外斜视平均结膜眼红指数为0．83±0．37，内斜视平均结膜眼红指数为2．03±0．90。同种斜视类型不同性别间比较，各种眼表指数均无统计学差异，同性别不同斜视类型间比较，内斜视泪河高度、第一次BUT、结膜眼红指数均与外斜视有显著性差异。随年龄增长，斜视患者的结膜眼红指数均增长。结论斜视患者均具不同程度的泪膜不稳定及炎症。内斜视患者较外斜视眼表健康情况更差。应重视斜视术前眼表的检查，防止围手术期发生眼表并发症。

Objective To investigate the state of tear film of patients with horizontal strabismus disease. Methods The conditions of ocular surface of 82 patients with extropia and 67 with esotro- pia were examined by Oculus anterior segment analyzer, including tear meniscus height, tear menis- cus height after irritation, redness index, non-invasive BUT, average BUT. Results The tear menis- cus height in the exotropia patients was 0.21±0.06mm, and that of esotropia was 0.17±0.05mmmm. The first BUT and average BUT of all patients were less than 6s and 7s. The average conjunctival index of exotropia and esotropia were 0.83±0.37 and 2.03±0.90 respectively. For the same gender, esotropia patients had a worse ocular surface condition than exotropia. Conjunctival redness index were bigger along with age increase for both strabismus. Conclusions Patients are combined with dry eye and inflammation beside strabismus. Ocuiar surface examination should be paid attention to before operation in order to prevent complications around operation.