急性脑梗死患者TICI脑血流动力学评估临床研究

MRA-TICI evaluation of cerebral hemodynamics in patients with acute cerebral infarction

目的探讨急性脑梗死患者MRA-TICI分级与神经功能缺损的关系,以及危险因素对TICI分级的影响。方法对脑梗死患者采用MRA进行TICI分级,分析患者危险因素,同时评价患者NIHSS评分及Barthel指数。结果LDL-C水平与TICI分级相关,LDL-C数值越小,TICI分级越高(P=0.011),常见危险因素(年龄,既往吸烟史、饮酒史,既往患高血压病、糖尿病,TG、CHOL、FPG)与MRA-TICI分级之间无相关性,患者的神经功能缺损程度、Barthel指数与MRA-TICI分级之间具有相关性,MRA-TICI分级越高,NIHSS评分越低,Barthel指数越高,其预后越好。结论 MRA-TICI分级可用来对急性脑梗死患者进行风险预测,判断其预后。

Objective To discuss the relationship between MRA-TICI grade and neurological impairment,evaluate the impact of common risk factors.Methods Select patients with acute ischemic stroke.All the patients underwent MRA examination.Use MRA-TICI grade evaluation the cerebral hemodynamics,collect the NIHSS score,Barthel index and common risk factors,perform a statistical analysis about them.Results LDL-C between MRA-TICI grade was statistically significant（P=0.011）,that the higher grade of MRA-TICI,the lower numerical value of LDL-C.While the common risk factors,just like age,smoking,drinking,hypertension,diabetes,TG,CHOL,FPG,between MRA-TICI were not statistically significant.The degree of neurological impairment and Barthel index between MRA-TICI was statistically significant,the higher grade of MRA-TICI,the lower the NIHSS score,the higher Barthel index,patients with better outcomes.Conclusion The risk indicators for patients with acute ischemic stroke could assess by the MRA-TICI grade system.In that regard,MRA-TICI can judge the outcome.