三亚市4047人乙肝感染的流行病学调查及结果分析

目的了解旅游城市三亚的乙肝感染现状,对乙肝两对半表型分布进行分析,为针对这些人员进行有效干预、预防及治疗提供数据支持。方法选取2014—2015年来武警三亚疗养院体检的4 047人作为研究对象,采用酶联免疫法(ELISA)检测乙肝两对半血清学结果。采用统计学软件SPSS 19.0对数据进行分析,率的比较采用χ~2检验,以P<0.05为差异具有统计学意义。结果此次调查乙肝感染率平均1.98%,具有8种乙肝表型,年轻人感染率相对较高,年龄越低感染率越高,公职人员感染率低于旅游服务人员,性别上无明显差异,感染以"小三阳"多见。结论年龄较低的旅游从业人员是三亚市乙肝管控的重点人群,需要加强对这类人员健康宣教及管控。

Objective To study the status of Hepatitis B virus（HBV） infection in the tourist city of Sanya, analyze the phenotype distribution of two pairs of semi-hepatitis B, so as to provide data support for effective intervention, prevention and treatment.Methods 4 047 people coming to People＇s Armed Police Sanya Sanatorium for health exam- ination from 2014 to 2015 were selected as the research objects,and Enzyme-linked immunosorbent assay（ELISA） was adopted to detect the serological results of two pairs of semi-hepatitis B.SPSS19.0 was adopted to conduct the da- ta analysis.Chi-square test was adopted for rate comparison, and P〈0.05 means the difference of statistical signifi- cance. Results The average infection rate of HBV was 1.98%, there were 8 kinds of HBV phenotypes, the infection rate among the young people was relatively high, the lower the age the higher the infection rate, the infection rate of civil servants was lower than that of tourist service personnel, there was no obvious difference between sexes, and the main infection type was small three positive.Conclusion Low-age tourist service personnel are the focus population of Hepatitis B control in Sanya City, so health education and control for the personnel should be strengthened.