2010-2014年常德市吸毒人群丙肝感染情况及相关危险因素调查

Prevalence of HCV infection and related risk factors among drug users in Changde City,2010-2014

目的调查分析常德市吸毒人群HCV感染情况及其危险因素。方法 2010-2014年采用整群抽样法,对常德市吸毒人群进行匿名问卷调查,拟合多因素Logistic回归模型探讨HCV感染的危险因素。结果接受调查的2 000名吸毒者,HCV感染阳性率为54.9%,其中静脉吸毒者HCV感染率78.7%。多因素logistic回归分析结果表明,静脉吸毒和共用针具与HCV感染率密切相关,并且静脉吸毒和共用针具时间越长,感染率越高。结论 2010-2014年常德市吸毒人群HCV感染率呈上升趋势,静脉吸毒和共用针具是HCV感染的危险因素。

Objective To investigate and analyze the prevalence of HCV infection and its risk factors among drug users in Changde City. Methods The objects were recruited by cluster samlping method in 2010-2014. Demographic and behavioral information was obtained by an anonymous questionnaire survey. Multi-factor logistic regression model was used to analyze the risk factors of HCV infection. Results The HCV infection rate of the 2,000 drug users surveyed was 54.9%, with the HCV infection rate of 78.7% in the injected drug users. Multi-factor logistic regression analysis showed that intravenous drug abuse and sharing needles were closely associated with the HCV infection rate; moreover, the longer the time of injecting drug abuse and sharing needles, the higher the HCV infecton rate. Conclusions The infecton rate of HCV in drug users in Changde City shows an increasing tendency from 2010-2014. Intravenous drug abuse and sharing needles are the risk factors for HCV infection.