认知干预改善阿尔茨海默病患者认知功能障碍及生活质量的效果研究

The effect of cognitive intervention on improving cognitive impairment and quality of life of patients with Alzheimer disease

目的探讨认知干预改善阿尔茨海默病患者认知功能障碍及生活质量的效果。方法选取160例阿尔茨海默病患者按照随机数字法分为实验组与对照组,各80例。对照组采用常规护理干预,实验组在对照组基础上采用认知干预,比较2组患者生存质量、认知功能、运动功能及生活独立率。结果干预3个月、6个月后,2组患者各生存质量指标得分较干预前均有不同程度提高,差异有统计学意义(P<0.05),且实验组各指标显著优于对照组,差异有统计学意义(P<0.05)。干预后,实验组认知功能及运动功能显著优于对照组,差异有统计学意义(P<0.05)。实验组患者的独立率显著优于对照组,差异有统计学意义(P<0.05)。结论认知干预能帮助阿尔茨海默病患者延缓病症的进一步发展,控制临床症状,减少对他人的依赖,降低肢体废用程度,提高运动功能,有效改善患者的认知功能障碍及生活质量。

Objective To explore effect of cognitive intervention on improving cognitive im- pairment and quality of life of patients with Alzheimer disease. Methods A total of 160 Alzheimer＇s disease patients in our hospital randomized into experimental group and control group, with 80 cases in each group. The control group received routine nursing intervention, and the experimental group received cognitive intervention on the basis of the control group, quality of life, cognitive function, motor function and independent living rate were compared. Results After three months and six months of intervention, quality of life score of two groups was greatly improved compared with intervention before, and the experimental group improved more than the control group （ P 〈 0.05 ）. After intervention, the experimental group had better cognitive function and motor function than the control group, the difference was statistically significant （ P 〈 0.05 ）. Independent rate of the experimental group was significantly better than the control group （P 〈 0.05 ）. Conclusion The cognitive intervention can delay further development of disease, control clinical condition, reduce dependence on others, reduce the degree of limb disuse, and improve motor function, which can effectively improve cognitive function impairment and quality of life of patients with Alzheimer disease.