低钙血症与早产儿感染的临床分析

Analysis on hypocalcemia and preterm infection

目的研究低钙血症与早产儿感染的关系,探讨血钙与早产儿感染严重程度及预后的相关性。方法将符合早产儿感染标准的125例患儿,记录住院期间内血钙值的变化,分为正常血钙组与低钙血症组,①统计白细胞数、PCT及CRP水平;②统计多器官功能障碍综合征(MODS)的发生率及死亡率;③统计无创通气(NCPAP)组与机械通气组血钙水平变化。结果①低钙组与正常血钙组白细胞水平差异无统计学意义(P>0.05),低钙血症组PCT及CRP水平高于正常血钙组(P<0.05);②低钙组与正常血钙组多器官功能障碍综合征(MODS)的发生率的比较有显著性差异(P<0.05),两组死亡率的比较差异无统计学意义(P>0.05);③无创通气组与机械通气组的血钙水平差异有统计学意义(P<0.05)。结论血钙水平反映早产儿感染的病情严重程度及预后,可作为判断早产儿感染预后情况的可靠指标之一。

Objective To explore the relationship between hypocalcemia and preterm infection, and the severity of in- fection and prognosis. Methods 125 infected preterms were divided into normal serum calcium group and hypoeal- cemia group, all were recorded changes in serum calcium values during hospitalization.① Statistical the value of white blood cell, PCT, CRP;②Statistical multiple organ dysfunction syndrome （MODS） incidence and mortality ;③ Statis- tical non-invasive ventilation （NCPAP） group with mechanical ventilation calcium levels. Results ①There is no dif- ferences of White blood cell between hypocalcemia and normal group （P〉0.05）. The value of PCT and CRP in Hypocalcemia was higher than normal group ; ②Normal group and Hypocalcemia group had significant difference in the incidence of MODS （P〈0.05）, While had no difference in mortality （P〉0.05）. ③NCPAP group and mechanical ventilation group also had significant difference in calcium levels （P〈0.05）. Conclusions Calcium levels in preterms reflects the severity of infection and prognosis, can be a reliable indicator of prognosis in infected preterms.