摘要
姜黄素是从传统中草药姜黄、郁金和莪术等姜黄科植物根块中提取的有效成分,大量研究证明,姜黄素具有抗氧化、抗炎、抗癌、清除自由基、抗微生物以及对心血管系统、消化系统等多方面药理作用,尤其对于多种肺癌细胞产生、增殖、侵袭转移以及增强克服多药耐药均具有抑制作用。文章综述了姜黄素在肺癌领域的研究现状,以期推动姜黄素在肺癌治疗领域的发展,探寻新的肺癌治疗方向。
Curcumin is the main active ingredient of extract from roots and stem of Chinese herbs Turmeric, curcuma zedoary and curcuma aromatic. Previous studies had shown that curcumin was useful in anti - oxidant, anti - inflammatory, anti - tumor, e- liminating the free radical, anti - microbial and multi - Pharmacological action of cardiovascular system and alimentary system. Curcumin exhibits growth, anti - process activity against a variety of cancer cells and overcoming multidrug resistance. This review presents an overview of the current studies of curcumin in lung cancer to improve the curative effects of curcumin in treating lung cancer and offer new directions for lung cancer treatment.
出处
《辽宁中医杂志》
CAS
北大核心
2017年第2期419-422,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81402988)
上海市普陀区临床重点专科建设项目
上海市普陀区领军人才项目
普陀区中心医院科研创新计划(2013GQ006I)
培英人才计划(2013SR1262)
关键词
姜黄素
肺癌
肿瘤抑制
多药耐药
eurcumin
lung cancer
tumor suppression
multidrug resistance