呼吸道感染患儿肺炎支原体IgM抗体检测结果分析

Analysis of mycoplasma pneumoniae Ig M antibody in children with respiratory tract infection

目的探讨呼吸道感染患儿肺炎支原体(mycoplasma pneumoniae,MP)阳性率与性别、季节、年龄和年度的关系,了解患儿感染肺炎支原体的流行趋势,为临床提供预防和治疗的依据。方法对2013-01至2015-12武警广东总队医院3011例血清样本MP-Ig M抗体检测结果进行回顾性分析。结果男性患儿MP-Ig M阳性率为19.53%,女性患儿MP-Ig M阳性率为26.76%,两组对比差异有统计学意义(P<0.01);MP-Ig M阳性率在不同年龄段和季节组之间差异有统计学意义(P<0.05),以3~<6岁、第一季度高发;2013、2014、2015年MP-Ig M阳性率分别为32.99%、20.20%、11.21%,差异有统计学意义(P<0.01)。结论肺炎支原体感染存在性别、年龄、季节和年度流行差异,第一季度、3~6岁女性患儿为高发,应有针对性地进行重点检测与防治。

Objective To study the correlation between the positive rate of mycoplasma pneumonia with gender,age,the season and year in children with respiratory tract infection in order to provide reference for prevention and clinical treatment.Methods 3011 serum samples detected with MP-Ig M antibody between 2013 and 2015 were retrospectively analyzed. The relationship between the positive rate of MP-Ig M antibody and gender,age,the season and year was studied. Results The positive rate of MP-Ig M antibody was 19. 53% among male children,and 26. 76% among female children. There was statistically significant difference between the two groups（ P〈0. 01）. There was statistically significant difference in the positive rate of MP-Ig M antibody between different age groups and season groups（ P〈0. 05）. The 3 ~ 6 years group and the first season group had the highest positive rates. The positive rate of MP-Ig M antibody in 2013,2014 and 2015 was 32. 99%,20. 20%,and 11. 21% respectively,and the difference was of statistical significance（ P〈0. 01）. Conclusions Mycoplasma pneumonia infection is related to gender,age,seasons and years. In the first season,female children aged three to six should be taken good care of.