基于“乙癸同源”理论探讨绝经后骨质疏松症的中医药治疗

The study of the treatment of postmenopausal osteoporosis with traditional Chinese medicine based on the theory of Yi and Gui sharing the same origin

绝经后骨质疏松症(PMOP)的西医治疗大多采用激素替代疗法(HRT),有良好的临床疗效,但副作用明显,中医药在骨质疏松症的治疗中具有疗效确凿及副作用小等明显优势,值得在临床推广应用。但如何探索有效的中医药治疗方案的经典指导理论,是发挥中医药治疗优势的重要内容。通过对古籍文献中"乙癸同源"理论的认识,探讨该理论与绝经后骨质疏松症的相关性,并与现代研究相结合,从该病的病因病机出发,基于"乙癸同源"的经典理论,针对肝肾亏虚的基本病因病机,发挥其对绝经后骨质疏松症治疗的理论指导作用,指导临床对绝经后骨质疏松症治疗的中医药使用,从根本上对患者进行中医药干预,能够达到治病求本的目的,为绝经后骨质疏松症的治疗提供有效的理论依据。

The treatment of postmenopausal osteoporosis（ PMOP） with the Western medicine uses hormone replacement therapy（ HRT） mostly. This treatment has a good clinical curative effect,but its side effect is obvious. Traditional Chinese medicine in the treatment of osteoporosis has obvious advantages in the conclusive efficacy and little side effect. The treatment is worth to apply in the clinics. However,to explore the classical guidance theory for the treatment with traditional Chinese medicine is important for the use of the advantages of traditional Chinese medicine. By studying the Yi and Gui sharing the same origin theory from ancient documents,we explore the correlation between the theory and postmenopausal osteoporosis,and combine it with modern research.From the etiology and pathogenesis of the disease and based on the Yi and Gui sharing the same origin theory,and focusing on the etiology and pathogenesis of asthenia of liver and kidney,the theory may play a theoretical guidance role in the treatment of postmenopausal osteoporosis,and guide the clinical treatment of postmenopausal osteoporosis based on traditional Chinese medicine.The theory may achieve fundamental intervention with Chinese medicine and provide effective theory basis for the treatment of postmenopausal osteoporosis.