全胸腔镜下肺叶切除术在早期非小细胞肺癌治疗中的疗效及安全性

Efficacy and safety of thoracoscopic lobectomy in the treatment of early non-small cell lung cancer

目的评价应用全胸腔镜肺叶切除术早期非小细胞肺癌临床疗效及安全性。方法选取2013年4月至2016年5月我院胸外科收治的早期非小细胞肺癌患者120例,按照治疗方法分为观察组(60例)与对照组(60例),观察组患者行全胸腔镜下肺叶切除术,对照组患者行常规开胸肺叶切除术,比较2组患者术中出血量、手术时间、住院时间、胸腔引流时间、淋巴结清扫数目及术后并发症发生情况。结果与对照组比较,观察组患者的术中出血量明显降低,手术时间、住院时间显著缩短,差异均有统计学意义(P<0.05);2组胸腔引流时间差异无统计学意义(P>0.05);2组患者的总引流量、淋巴结清扫数目、围术期死亡率比较差异均无统计学意义(P>0.05);观察组并发症总发生率为3.33%,对照组并发症总发生率为25.00%,差异有统计学意义(P<0.05)。结论全胸腔镜下肺叶切除术应用于早期非小细胞肺癌患者的治疗,能够显著改善患者手术情况,有助于术后恢复,降低并发症,值得临床推广。

Objective To evaluate the clinical efficacy and safety of thoracoscopic lobectomy in the treatment of early non -small cell lung cancer .Methods One hundred and twenty cases of early non-small cell lung cancer admitted into Leshan Hospital from April 2013 to May 2016 were recruited as study subjects , and were equally divided into the observation group （n=60） and the control group （n=60）, in accordance with different treatment methods .The patients in the observation group underwent thoracoscopic lobecto-my, while the patients in the control group received lobectomy via conventional thoracotomy .Blood loss during surgery , surgical time, duration of hospitalization , duration of chest tube drainage , lymph node dissection number and rate of postoperative complication were compared between the patients of the 2 groups.Results When compared with that of the control group , blood loss during surgery for the patients of the observation group was significantly reduced , surgical time and duration of hospitalization were obviously shortened .Statis-tical significance could be seen, when comparisons were made between the 2 groups（P〈0.05）.There was no statistical significance in the duration of chest tube drainage for the patients of the 2 groups（P〉0.05）.Statistical significance could neither be seen in total a-mount of chest tube drainage , the number of lymph node dissection , and the rate of perioperative mortality in the patients of the 2 groups （P〉0.05）.The rate of complication for the patients of the observation group was 3.33%, while that of the control group was 25.00%, and statistical significance could be seen , when comparisons were made between the 2 groups（P〈0.05）.Conclusion The application of thoracoscopic lobectomy in the treatment of non-small cell lung cancer could significantly improve surgical effect , hasten patient recovery and decrease rate of complication after surgery .For this reason , it was worth further clinical extension .