1例境外输入性恶性疟配子体的检出

Detection of a case of imported falciparum malaria gametocyte

目的了解恶性疟配子体发生、发展原因及检出经过。方法根据流行病学调查及疟疾血检结果对1例疟疾案例进行分析。结果报道了1例境外输入性恶性疟病例的诊疗情况。患者非洲务工1年,感染疟疾数次,回国前再次发病并在当地抗疟治疗6 d,10 d后回国再次感到发热、出汗、头痛。到乳山疾控中心采血镜检,后经威海市疾控中心复核及山东省寄生虫病防治研究所疟疾诊断参比实验室复核,确诊为恶性疟。因为及时给予患者科泰复药物治疗,痊愈,3个月随访,未见异常。结论由于近几年对疟疾认识的提高,早发现早治疗使得恶性疟很少发展成配子体,因此恶性疟配子体的检出显得弥足珍贵。

Objective To investigate the cause, development and detection of plasmodium falciparum.Methods To analyse 1 cases of malaria according to the epidemiological investigation and the results of malaria blood test. Results A case of overseas imported falciparum malaria was reported in Rushan. The patient worked in Africa for a year, when he had infected malaria several times. Before returned to China, he infected malaria again and was treated with artesunate injection for six days. After ten days, he came back to China and felt fever, sweating and headache again. The patient was diagnosed as falciparum malaria by a blood test in Rushan Center for Disease Control and Prevention, reviewed by Weihai CDC and Shandong Institute of Parasitic Diseases＇ malaria diagnosis and reference laboratory. The patient was cured for treatment with Duo-Cotecxin. The malaria had not recurred for the 3-month follow-up. Conclusion In recent years due to the improving of malaria awareness, early detection and treatment of the malignant malaria rarely develop into gametophytes, therefore falciparum gametocyte detection is precious.