人参蛤蚧散加减对慢性阻塞性肺疾病缓解期患者肺功能及生活质量的影响

Effect of Ginseng Gecko Powder on the Pulmonary Function and Quality of Life in Patients with Stable COPD

目的:观察人参蛤蚧散对慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)缓解期患者肺功能及生活质量的影响。方法:120例COPD缓解期(肺肾气虚证)患者随机平分为对照组和观察组,每组60例。对照组给予支气管扩张剂等常规治疗,观察组在对照组治疗基础上服用人参蛤蚧散。3个疗程后比较两组患者的肺功能、圣乔治呼吸问卷(Stgeorge's respiratory questionaire,SGOR)评分及临床疗效。结果:治疗后,两组患者的最大用力呼气中期流速(maximal mid-expiratory flow velocity,MMEF)、呼气峰流速值(peak expiratory flow,PEF)、第1秒用力呼气量(forced expiratory volume in 1 second,FEV1)、第1秒用力呼气量/用力肺活量(forced vital capacity,FVC)指标均较治疗前显著改善,观察组患者上述各指标改善程度显著优于对照组患者(P<0.05);观察组SGOR总评分比对照组显著下降(P<0.05);观察组有效率为90.00%,明显优于对照组68.33%(P<0.05)。结论:人参蛤蚧散治疗缓解期COPD(肺肾气虚证)患者的疗效显著,能减轻患者的临床症状及疾病的干扰,提高患者活动能力,有效提高患者的生活质量。

Objective：To observe the effect of Ginseng Gecko Powder on the pulmonary function and quality of life in patients with stable COPD. Method：120 cases of patients with stable COPD （lung and kidney Qi deficiency syndrome） were randomly average divided into the control group and the experimental group. The control group used routine treatment and the experimental group used Ginseng Gecko Powder on the basis of control group. Observed and compared the pulmonary function and SGOR score in the two groups after 3 courses. Results：The MMEF,PEF, FEV1, FEV1/FVC and total effective rate of experimental group were all bet- ter than those of control group（ P 〈 0.05 ）. SGOR score of the experimental group was more lower than cont,＇ol group（ P 〈 0.05）. Conclusion：Ginseng Gecko Powder can improve pulmonary function and quality of life ,relieve their symptoms in patients with stable COPD.