狼疮性肾炎中医辨证分型与实验室检查相关性分析

Correlation Analysis of TCM Syndrome Differentiation and Laboratory Examination of Lupus Nephritis

目的:分析狼疮性肾炎(lupus nephritis,LN)中医辨证分型与实验室检查之间的相关性,为今后制定标准化的中医诊疗方案提供依据。方法:运用回顾性调查研究方法,选择220例LN住院患者,对其中医辨证分型与实验室检查之间进行数据分析,结合医学专业知识探讨两者之间的相关性。结果:LN的中医辨证分型以脾肾阳虚型为主,LN中医辨证分型与24 h尿蛋白定量之间存在相关性,与血肌酐、抗ANA抗体、抗ds-DNA抗体、抗Sm抗体无相关性。结论:LN中医辨证分型与实验室检查存在一定的相关性,需要进一步深入研究。

Objective：To study the clinical data of patients with Lupus Nephritis （LN） hospitalized in the first and third affiliated hospitals to Henan University of Chinese Medicine, and to summarize the correlation between the Syndrome differentiation of LN and laboratory tests. Methods ： The retrospective investigation method was used and 220 cases of patients of lupus nephritis hospital- ized in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine were selected. The correlation between the Syndrome differentiation of LN and the laboratory tests was explored. Results ： Most of the LN cases are Spleen and Kidney Yang deficiency in Syndrome. There was correlation between TCM Syndrome type and 24-hour urinary protein, but not with serum creati- nine, anti-ANA antibody, anti-ds-DNA antibody and anti-Sm antibody. Conclusion：There is correlation between TCM syndrome classification and laboratory examination, and further study is needed.