肺炎支原体感染与小儿支气管哮喘发病的相关性研究

Correlation study between mycoplasma pneumoniae infection and the incidence of bronchial asthma in children

目的:对小儿支气管哮喘的发病与肺炎支原体感染之间的关联性进行探究。方法:选取儿科门诊及病房收治的120例患儿为研究对象,按照支气管哮喘诊断标准,观察组为患有支气管哮喘的60名患儿,而对照组为近期患有呼吸道感染的60名患儿。对120名患儿的血清样本进行肺炎支原体抗体浓度检测并做好记录,分析两组患者的数据结果。结果:60例支气管哮喘患儿中,有29例血清肺炎支原体抗体(mycoplasma pneumoniae,MP-Ig M)阳性,阳性率为48.3%;而60例对照组患儿中有11例血清肺炎支原体抗体(MP-IgM)阳性,阳性率为18.3%,两组比较差异有统计学意义(χ~2=12.15,P=0.000,P<0.01)。结论:对小儿支气管哮喘发作期应考虑为MP诱发的可能,因此在临床工作中我们对患儿进行MP-IgM检测可有助于该病的治疗。

Objective：To explore the association between the incidence of bronchial asthma and the infection of mycoplasma pneumonia in children. Methods： 120 cases were selected from the department of pediatrics as the research objects,60 children with bronchial asthma in observation group and 60 children with respiratory tract infection in control group according to the diagnostic standard of bronchial asthma. The mycoplasma pneumoniae antibody concentration detection was made to detect the serum samples of the 120 children,and the data of the two groups were analyzed. Results： Among the 60 cases of bronchial asthma children,29 cases of serum mycoplasma pneumonia antibody（ MP- Ig M） were positive,with the positive rate at 48. 3 %; 11 cases of MP- Ig M were positive in control group,with the positive rate at 18. 3 %. There was significant difference between the two groups（ χ2= 12. 15. P = 0. 000,P〈0. 01）. Conclusion： The incidence of bronchial asthma should be taken into account to induce mycoplasma pneumonia in children. Therefore,MP- Ig M detection in the clinical work can contribute to the treatment of the disease.