ADT类[铁铁]氢化酶全羰基模型物的合成研究进展

Progress in the Synthesis of Diiron Azadithiolato Hexcarbonyls as Models for the [FeFe]-Hydrogenase

自然界中的[铁铁]氢化酶高效催化质子还原产氢的能力为发展生物制氢技术解决能源危机带来了希望。合成[铁铁]氢化酶模型物并研究其催化性质,不仅有助于深入了解[铁铁]氢化酶的催化制氢机理,找到影响制氢效率的关键因素,还能够为设计合成高效、稳定的制氢催化剂提供有效途径,从而推动仿生制氢技术的发展,帮助人类解决所面临的能源紧缺和环境污染等问题。文章系统总结了ADT类[铁铁]氢化酶全羰基模型物的各种制备方法,描述了各种制备方法的优缺点和其应用范围。期望能够加深对ADT类[铁铁]氢化酶模型物这一研究领域的了解,为今后该类模型物的合成研究提供指导。

[ FeFe ]-Hydrogenase brings the hope to develop biological hydrogen production technology and solve the problem of energy crisis because of its catalytic ability and high efficiency of reduction of proton. Studies on the syntheses and catalytic properties of [ FeFe ]-hydrogenase models will not only enrich a systematic understanding of the mechanism of enzyme-catalyzed reaction of producing hydrogen and find the key factors of affecting catalytic efficiency, but also provide an effective route to design and synthesize high efficient and stable catalysts for hydrogen production. Furthermore, it will promote the development of biological hydrogen production technology and help us to solve the problems of energy crisis and environmental pollution. This paper systematically summarizes the syntheses of diiron azadithiolato hexcarbonyls as active site models for the [ FeFe ] -hydrogenase, and the various advantages as well as disadvantages of those methods. This review is anticipated to deepen the understanding of the research field where diiron azadithiolato hexcarbonyls as active site models for the [ FeFe ] -hydrogenase and hence provide guidance for the syntheses of those models.