急性冠状动脉综合征患者血清中介素水平及其临床意义

Clinical Significance of Serum Adiponectin of Levels in Patients with Acute Coronary Syndrome

目的:研究急性冠状动脉综合征(ACS)患者血清中介素(IMD)的水平以及临床价值。方法:选取2015至2016年的ACS患者40例作为观察组,同时选择健康体检者40例作为健康对照组,检测两组患者的IMD以及超敏C反应蛋白(hs-CRP)指标,以冠状动脉造影结果结合Gensini积分进行冠状动脉狭窄评估,以Pearson相关分析方法评价IMD与各项指标的相关性。结果:观察组患者IMD与hs-CRP水平均明显高于对照组(P<0.01),血清IMD水平与Gensini积分以及hs-CRP水平均保持正相关(P<0.01)。结论:ACS患者血清IMD水平明显高于健康人群,与冠脉病变病情进展存在密切的关系,可以作为ACS诊断以及预后评价的有效标志物。

Objective： To study the clinical value of serum adiponectin of levels in patients with acute coronary syndrome. Methods ： 40 cases of ACS patients treated in our hospital from 2015 to 2016 were selected as observation group, and 40 cases of healthy as healthy control group. IMD and hypersensitive c-reactive protein （ hs - CRP ） indicator, with the result of coronary angiography, the Gensini score assessment of coronary artery stenosis with Pearson correlation analysis method to evaluate the IMD and the correlation of the indicators to be detected. Results： IMD and hs - CRP levels of observation group patients were significantly higher than that of control group （ P 〈 0.01 ） , serum level of IMD and Gensini score and hs - CRP levels were maintaining positive correlation （P 〈 0.01 ）. Conclusion： The level of serum IMD in patients with ACS is significantly higher than that in healthy people, which is closely related to the progression of coronary artery disease. It could be used as an effective marker for ACS diagnosis and prognosis evaluation.