受体阻滞剂联合用药及单用治疗膀胱过度活动症合并膀胱出口梗阻的效果比较

Comparison between combined administration of receptor blockers and single administration of receptor blocker in the treatment of patients with overactive bladder syndrome and bladder outlet obstruction

目的比较α受体阻滞剂联合用药及单用治疗膀胱过度活动症合并膀胱出口梗阻的疗效。方法选取100例膀胱过度活动症合并膀胱出口梗阻患者,随机分为2组。对照组患者采用α受体阻滞剂进行治疗,研究组患者采用α受体阻滞剂联合M受体阻滞剂的治疗方式,比较2组治疗效果。结果研究组患者治疗后的疼痛评分、排尿评分、总积分显著低于对照组患者(P<0.05)。对照组患者治疗后OABSS评分为(7.2±1.5)分,研究组患者治疗后OABSS评分为(4.8±1.2)分,差异有统计学意义(P<0.05)。研究组患者并发症发生率为4.0%,显著低于对照组患者的10.0%(P<0.05)。结论在膀胱过度活动症合并膀胱出口梗阻患者的临床治疗中,受体阻滞剂联合用药具有更好的治疗效果。

Objective To compare the efficacy of combined administration of receptor blockers and single administration of receptor blocker in the treatment of patients with overactive bladder syndrome and bladder outlet obstruction. Methods A total of 100 patients with overactive bladder syndrome and bladder outlet obstruction were randomly divided into two groups. Control group was treated with α receptor blocker,while study group was treated with α receptor blocker and M receptor blocker. Therapeutic effect was compared. Results The pain score,urinary score and total score of the study group were significantly lower than those of the control group（ P〈0. 05）. After treatment,OABSS score in the control group was（ 7. 2 ± 1. 5）,which was significantly higher than（ 4. 8 ± 1. 2）in the study group（ P〈0. 05）. The incidence rate of complications in the study group was 4%,which was significantly lower than 10. 0% in the control group（ P〈0. 05）. Conclusion In the clinical treatment of patients with bladder outlet obstruction,the combination of receptor blockers has a better therapeutic effect.