串联药物洗脱支架治疗冠状动脉弥漫性长病变的远期疗效

The Long-term Efficacy of Overlapping Drug-eluting Stent in the Treatment of Coronary Artery Diffuse Long Lesions

目的:评价串联药物洗脱支架(DES)治疗冠状动脉弥漫性长病变的远期临床疗效。方法:回顾性分析233例冠状动脉弥漫性长病变且成功接受串联DES置入术或单个长DES置入术的冠心病患者,根据置入支架方式及长度的不同,分为A组:置入串联DES且支架总长度34-59mm(n=85);B组:置入串联DES且支架总长度60-95mm(n=71);C组:置入单个长DES且支架长度35-38mm(n=77)。比较各组术后第1年和第2年主要不良心血管事件(MACE)和支架内再狭窄(ISR)发生率的差异。结果:术后第1年和第2年,三组间MACE和ISR的发生率差异无统计学意义(P>0.05)。结论:串联DES且支架总长度≥60mm治疗冠状动脉弥漫性长病变的远期临床疗效总体满意,安全可行。

Objective：To evaluate the long-term clinical efficacy of overlapping drug-eluting stent（DES）in the treatment of coronary artery diffuse long lesions.Method：A total of 233 patients with coronary artery diffuse long lesions who accepted overlapping DES or single long DES during percutaneous coronary intervention（PCI）were analyzed retrospectively and were divided into 3groups according to the difference of the way and the length of stents implanted：group A：patients accepted 34-59 mm overlapping DES（n=85）,group B：patients accepted 60-95 mm overlapping DES（n=71）,group C：patients accepted 35-38 mm single long DES（n=77）.The incidence of mayor adverse cardiac events（MACE）and in-stent restenosis（ISR）of each group was analyzed respectively in the first and second year after PCI.Results：In the first and second year after PCI,the incidence of MACE and ISR between group A and C had no statistical significance（P〉0.05）;compared with group C,the incidence of MACE and ISR of group B tended to increase,but the difference also had no statistical significance（P〉0.05）.Conclusion：The long-term clinical efficacy of overlapping DES（the total length≥60mm）is satisfactory in the treatment of coronary artery diffuse long lesions.