中医辨证论治痤疮84例

Eighty-Four Cases of Acne Treated Based on Syndrome Differentiation

目的:观察中医辨证论治痤疮的临床疗效及安全性。方法:选择本院2012年1月—2013年12月诊治的168例痤疮患者为研究对象,随机分为对照组和观察组各84例。对照组采用维生素B6、罗红霉素和外用擦剂等方法治疗,观察组运用中药方剂治疗,两组患者均以15 d为1个疗程,治疗2个疗程后对其疗效与安全性进行评价。结果:观察组有效率为95.2%,对照组有效率为83.3%,观察组有效率明显高于对照组,差异显著(P<0.05);观察组的雄激素受体水平为(19.8±3.8)mg,明显低于对照组的(28.4±8.9)mg,差异显著(P<0.05);观察组不良反应发生率也明显低于对照组,差异具有统计学意义(P<0.05)。结论:中医辨证论治痤疮不仅临床疗效显著,安全可靠,而且能够美容养颜,提高患者的生活质量。

Objective ： To observe the clinical curative effect of treatment based on syndrome differentiation on ache and its safety. Methods ： One hundred and sixty-eight patients with ache who were treated in our hospital between Jan. of 2012 and Dec. of 2013 were chosen as the research subjects, and randomly divided into the control group and the observation group, with 84 causes in each grnup. The ones in the control group were given routine Western medicine treatment, including Vitamin B6, roxithromycin and topical liniment, while the ones in the observation group were treated with TCM formula. Both groups regarded 15 days as one course, then the clinical curative effects of the two groups and safety were evaluated after 2 courses. Results： In the observa- tion group, 61 cases were markedly effective, 22 cases were effective, 1 was ineffective, and the effective rate was 95.2% ; while the effective rate of the control group was 83.3% , the observation group was higher than that of the control group, the difference between Ihem was significant （P 〈 0.05）. Through analysis and comparison of the efficacy of ache in patients with spleen-stomach damp beat syndrome, lung meridian wind-heat syndrome, yin deficiency of liver and kidney syndrome, syndrome of stagnation of liver qi respectively, the differences between them were statistically significant （P 〈 0.05 ）. The positive rate of androgen receptor in the observation group was （ 19.8 - 3.8） % , which was significantly lower than that of the control group （28.4 ± 8.9 ） % , and the difference was significant （ P 〈 0.05 ）. The incidence of adverse reactions in the observation group was significantly lower than that in the control group, the difference was statistically significant （P 〈0. 05 ）. Conclusion： The use of traditional Chinese medicine therapy in the treatment of ache nut only has a remarkable curative effect, but also is safe and relia- ble, can maintain beauty and keep young, improve the quality of life of patients.