细菌感染性腹泻216例临床及病原学特点

Clinical and etiological characteristics of bacterial infectious diarrhea: Analysis of 216 cases

目的了解细菌感染性腹泻的临床及病原学特点.方法回顾性分析2012-2014年新疆医科大学第一附属医院216例感染性腹泻患者的临床及病原学特点.计数资料行χ2检验.结果3年间因感染性腹泻就诊的3215例患者中,216例粪细菌培养阳性,包括致病性大肠埃希菌(Escherichia coli,E.coli)感染112例(51.8%),志贺菌属感染64例(29.6%),副溶血弧菌感染23例(10.6%),沙门菌属感染17例(7.8%);腹泻就诊者在每年5-10 m o多见;致病性E.coli感染临床表现为腹痛、腹泻、恶心、呕吐,可伴有脱水,志贺菌属感染临床表现为发热、腹痛、腹泻、里急后重感.结论感染性腹泻患者粪细菌培养阳性率不高,仍以E.coli、志贺菌属为主,不同细菌感染腹泻患者临床表现有差异.

AIM To investigate the clinical and etiological characteristics of bacterial infectious diarrhea.METHODS The clinical and etiological characteristics of216 cases of infectious diarrhea collected in the First Affiliated Hospital of Xinjiang Medical University from 2012 to 2014 were analyzed retrospectively.Count data were compared using χ~2 test.RESULTS Of 3215 infectious diarrhea patients treated over the three years,216 had positive fecal bacterial culture,including 112 cases of pathogenic Escherichia coli（E.coli） infection（51.8%）,64 cases of Shigella infection（29.6%）,23 cases of Vibrio parahaemolyticus infection（10.6%）,and 17 cases of Salmonella infection（7.8%）.Diarrhea patients were seen more commonly in May and October each year.The clinical manifestations of pathogenic E.coli infection were abdominal pain,diarrhea,nausea,vomiting,and dehydration,while those of Shigella infection were fever,abdominal pain,diarrhea,and tenesmus.CONCLUSION The positive rate of fecal bacteria culture in patients with infectious diarrhea is low,and the diarrhea is caused mainly by E.coli and Shigella.There are differences in clinical manifestations between E.coli and Shigella infections.