2002-2015年上海市浦东新区育龄妇女恶性肿瘤死亡流行特征

Epidemiological characteristics of death caused by malignant tumor in the women of childbearing age in Pudong New Area of Shanghai from 2002 to 2015

目的了解2002-2015年浦东新区育龄妇女死亡情况及其趋势,为制定相应的干预措施提供参考。方法依据根本死因编码分析死因构成和顺位,对2002-2015年上海市浦东新区育龄妇女死亡资料进行流行病学分析,并应用Join-point线性回归法分析不同组别之间的死亡率时间变化趋势。结果 2002-2015年浦东新区育龄妇女恶性肿瘤死亡率为27.75/10万,总体死亡率呈现下降趋势(APC=-2.90%,P<0.001);其中,胃癌(APC=-3.01%,P=0.007)、乳腺癌(APC=-4.24%,P=0.008)、肺癌(APC=-5.92%,P=0.001)、肝癌(APC=-7.62%,P<0.001)死亡率逐年下降,宫颈癌死亡率呈现逐年上升趋势(APC=11.39%,P=0.007)。结论浦东新区育龄妇女恶性肿瘤死亡率呈现降低趋势,不同癌种变化情况存在差异,在日常肿瘤防控的基础上,应尤其注重针对宫颈癌的干预。

Objective To understand the mortality and death trend of the women of childbearing age in Pudong New Area of Shanghai from 2002 to 2015,provide reference for making corresponding intervention measures. Methods According to ICD-10 codes,the proportion and rank of death causes were analyzed,the death data of the women of childbearing age in Pudong New Area of Shanghai from 2002 to2015 was analyzed epidemiologically,Join-point linear regression method was used to analyze the change trends of mortality with time in different groups. Results The mortality of malignant tumor in the women of childbearing age in Pudong New Area of Shanghai from 2002 to2015 was 27. 75 per 100 000 persons,the total mortality showed a downward trend（ APC =-2. 90%,P〈0. 001）,the mortalities of gastric cancer（ APC =-3. 01%,P = 0. 007）,breast cancer（ APC =- 4. 24%,P = 0. 008）,lung cancer（ APC =- 5. 92,P = 0. 001） and liver cancer（ APC =-7. 62,P〈0. 001） decreased gradually year by year,while the mortality of cervical cancer increased year by year（ APC =11. 39%,P = 0. 007）. Conclusion The mortality of malignant tumor among the women of childbearing age in Pudong New Area showed a downward trend. The change trends of different malignant tumors were different. On the basis of general cancer prevention and control,more attention should be paid to cervical cancer prevention.