糖尿病与腹主动脉瘤的相关性研究进展

Progress in the study of the association between diabetes mellitus and abdominal aortic aneurysm

流行病学数据显示糖尿病是腹主动脉瘤的保护因素。糖尿病影响腹主动脉的生理学特性．降低腹主动脉瘤的发病风险及增长速度，但对腹主动脉瘤破裂、术后并发症及预后的影响尚有争议。糖尿病的治疗药物对腹主动脉瘤发生及进展的影响也有待于临床随机对照试验加以研究。本文对糖尿病与腹主动脉瘤的相关性研究进展进行综述。

Epidemiologic evidence suggests that diabetes mellitus appears to be negatively associated with abdominal aortic aneurysm formation. Diabetes mellitus may affect the physiological characteristics of the aorta and reduce the prevalence, incidence and expansion rate of abdominal aortic aneurysm. But the impact of diabetes mellitus on the rupture, operative complication and clinical outcome of abdominal aortic aneurysm is unclear. Randomized controlled trials are needed before conclusions can be drawn on the link between development and expansion of abdominal aortic aneurysm and medicines for diabetes. This review aims to analyze updated evidence of the association between diabetes mellitus and abdominal aortic aneurysm.