腹腔镜手术与甲氨蝶呤治疗输卵管妊娠临床效果比较

Effect of laparoscopic oviduct operation and Methotrexate therapy in treatment of tubal pregnancy

目的:比较腹腔镜手术与甲氨蝶呤治疗输卵管妊娠的临床效果。方法:选取我院收治的180例输卵管妊娠患者,分为腹腔镜手术治疗组和甲氨蝶呤化疗组,每组90例,比较分析两种治疗方法的治疗效果。结果:两种方法均可治愈输卵管妊娠患者,腹腔镜手术组治疗的治愈率为100%,显著高于甲氨蝶呤组治疗的治愈率(84.4%),两组比较差异明显(P<0.05);腹腔镜手术组β-HCG下降至正常时间、住院时间也明显短于甲氨蝶呤组,差异显著(P<0.05);输卵管通畅率和再次宫内妊娠率明显高于对照组,差异有显著性(P<0.05)。结论:与甲氨蝶呤治疗相比,腹腔镜手术具有明显优势,是输卵管妊娠治疗中一种安全、可靠的方法,值得在临床中值得推广和应用。

Objectives： To compare the clinical effect of laparoscopic oviduct surgery and Methotrexate therapy in treatment of tubal pregnancy. Methods： A total of 180 patients with tubal pregnancy were divided into two groups,laparoscopic oviduct surgery group（ n = 90） and Methotrexate therapy group（ n = 90）. The efficacy analysis and follow- up analysis were compared. Results： The cure rate of laparoscopic oviduct surgery and Methotrexate therapy was 100% and 84. 44% respectively. The time of hospitalization and the duration of postoperative β- HCG level till normal level were significant less than those of the Methotrexate therapy group（ P〈 0. 05）. The potency rate of common oviduct and conception rate of the observation group were significant higher than those of the control group（ P〈 0. 05）. Conclusion： Laparoscopic oviduct operation has advantages in treatment of tubal pregnancy compared with Methotrexate therapy. It is a safe and effective method,which is worth of applying in practice.