单纯放疗与同步放化疗治疗宫颈癌的临床近期疗效比较

Comparison of the Short-term Effects of Radiotherapy and Concurrent Radiotherapy and Chemotherapy in the Treatment of Cervical Cancer

目的研究单纯放疗和同步放化疗对宫颈癌患者进行治疗,对比观察其临床治疗效果。方法随机选取2014年2月~2016年1月进行治疗的局部晚期宫颈癌患者30例,根据其临床治疗方式的不同随机均分为研究组和对照组,15例研究组患者通过同步放化疗进行治疗,15例对照组患者通过单纯放疗进行治疗,对比两组患者临床治疗效果。结果研究组患者临床近期治疗有效率为86.67%,显著高于对照组患者53.33%的临床近期治疗有效率,组间比较差异显著具有统计学意义(P<0.05);两组患者均出现1级和2级消化道不良反应和骨髓抑制,研究组消化道不良反应和骨髓抑制总发生率分别为53.33%和66.67%,均显著高于对照组患者(26.67%和20.00%)(P<0.05)。结论相比较于单纯放疗治疗宫颈癌患者,同步放化疗治疗宫颈癌患者近期临床疗效更加显著。

Objective To study the radiotherapy and radiotherapy for patients with cervical cancer were treated with chemotherapy,compared to observe the effect of clinical treatment. Methods Randomly selected from February 2014 to January 2016 in our hospital for treatment of patients with locally advanced cervical cancer were randomly divided into 30 cases,according to different clinical treatment methods for the study group and control group,15 study group of patients treated by concurrent radiotherapy and chemotherapy treatment,15 patients in control group were treated by radiotherapy alone. The therapeutic effects in two groups were compared. Results The study group of patients with clinical therapeutic effective rate was 86. 67%,significantly higher than the control group of 53. 33% patients with recent clinical treatment efficiency,significant difference between the two groups was statistically significant（ P〈0. 05）; two patients were grade 1 and grade 2 adverse gastrointestinal reactions and bone marrow suppression,gastrointestinal adverse reactions in study group and the total incidence of bone marrow suppression points Do not 53. 33% and 66. 67%,are significantly higher than the control group patients（ 26. 67% and 20%）（ P〈0. 05）. Conclusions Compared with radiotherapy alone in patients with cervical cancer,concurrent chemotherapy and radiotherapy for cervical cancer patients in the near future clinical efficacy is more significant.