PVC类一次性使用导尿管的DEHP溶出量分析

Analysis the content of DEHP in PVC disposable catheter

采用GC-MS的方法对不同生产企业的8批PVC材质的导尿管中DEHP的含量以及各自不同浸提条件下的溶出量进行了测定。通过分析确认,各生产企业生产的PVC材质的导尿管中DEHP的游离量分别在112.8~208.0mg/g之间,浸提液溶出率在0.012‰~0.024‰之间。导尿管中DEHP在临床使用过程中有可能会不断释放,对人体健康具有潜在危害。

Determine the content of DEHP and the dissolution rate in different extraction conditonns in PVC disposable catheter by GC- MS. Through the analysis confirmed that the free DEHP of PVC disposable catheter in 112. 8 ~ 208. 0 mg / g,the extract dissolution rate at 0. 012 ‰ ~ 0. 024 ‰. DEHP in the catheter in in clinical use is likely to be constantly in the process of release,potentially harmful to human body health.