急性脱髓鞘脑病的临床症状表现与诊治分析

Clinical Symptoms Diagnosis and Treatment of Acute Demyelinating Encephalopathy Analysis

目的分析急性脱髓鞘脑病的临床症状表现与诊治成效。方法方便选择2012年4月—2015年3月该院收治的42例急性脱髓鞘脑病患者作为研究对象,分析其临床症状表现以及诊治效果。采用随机数法将其分为甲组和乙组各21例,甲组患者使用地塞米松治疗,乙组患者使用甲泼尼松治疗,对比两组患者的临床疗效。结果乙组患者的临床总有效率为95.24%,高于甲组的71.43%,对比差异有统计学意义(P<0.05);治疗期间均有不良反应发生,甲组为28.57%,乙组为23.81%,差异无统计学意义(P>0.05)。结论急性脱髓鞘脑病的临床症状表现主要为呕吐、癫痫等,影像学、脑脊液检查结果异常,使用甲泼尼松等激素治疗具有较好的效果,应引起重视。

Objective To analyze the acute demyelinating encephalopathy clinical symptoms, diagnosis and treatment effectiveness. Methods Convenient selection from April 2012 to March 2015 in 42 patients with acute demyelinating encephalopathy patients as research subjects, their clinical symptoms and the diagnosis and treatment. Method using a random number will be divided into groups A and B each 21 cases, patients treated with dexamethasone Group A, Group B patients with methylprednisolone therapy, clinical efficacy compared two groups of patients. Results Group B patients with clinical total effective rate was 95.24%, higher than 71.43% of Group A, compared to the results of a significant difference（P 0.05）;adverse reactions have occurred during treatment, 28.57% Group A, Group B 23.81% no significant difference（P 0.05）.Conclusion The clinical symptoms of acute demyelinating encephalopathy mainly vomiting, epilepsy, imaging, cerebrospinal fluid examination abnormal results, the use of methylprednisolone and other hormone therapy has a good effect, attention should be paid.