分析全静脉麻醉与吸入麻醉对老年患者术后认知功能的影响

Analysis of Effect of Total Intravenous Anesthesia and Inhalation Anesthesia on the Postoperative Cognitive Function of Senile Patients

目的分析全静脉麻醉与吸入麻醉对老年患者术后认知功能的影响。方法方便选择2015年5月—2016年5月于吉林省前卫医院行胃肠手术的老年患者180例,以随机数字表将其均分为研究组与对照组各90例。研究组采取全凭静脉麻醉,对照组采用吸入麻醉。通过MMSE量表检测2组患者术前、术后1、3、10 h及24 h的认知功能。结果研究组术后1 h、术后3 h及术后10 h时MMSE评分分别为(25.6±1.8)分、(28.4±1.2)分、(29.4±0.6)分,高于对照组的(22.4±1.8)分、(24.2±1.3)分、(25.0±1.2)分(P<0.05),研究组术后24 h时MMSE评分(29.4±1.3)分与对照组(28.4±1.5)分对比差异无统计学意义(P>0.05)。结论与吸入麻醉相比,全静脉麻醉对老年患者术后认知功能的保护作用更佳,适于临床推广。

Objective To analyze the effect of total intravenous anesthesia and inhalation anesthesia on the postoperative cognitive function of senile patients. Methods Convenient selection 180 cases of senile patients with gastrointestinal surgery from May 2015 to May 2016 were selected and randomly divided into two groups with 90 cases in each, the research group adopted the total intravenous anesthesia, while the control group adopted the inhalation anesthesia, and the cognitive functions before operation, at 1, 3, 10 h and 24 h after operation of the two groups were tested by the MMSE scale. Results The MMSE scores at 1, 3 h and 10 h after operation were respectively（25.6±1.8）scores,（28.4±1.2）scores and（29.4±0.6）scores,which were higher than those in the control group（22.4±1.8）scores,（24.2±1.3）scores and（25.0±1.2）scores（P0.05）, and there was no statistical difference in the MMSE score at 24 h after operation between the research group and the control group[（29.4±1.3）scores vs（28.4±1.5）scores]（P0.05）. Conclusion The protective effect of total intravenous anesthesia on the postoperative cognitive function of senile patients is better than that of the inhalation anesthesia, which is suitable for the clinical promotion.