钙泊三醇倍他米松软膏外用治疗寻常性银屑病的临床分析

Clinical Analysis of Calcipotriol Betamethasone Ointment for External Use in Treatment of Psoriasis Vulgaris

目的观察分析钙泊三醇倍他米松软膏外用治疗寻常性银屑病的临床效果。方法方便选取该院于2015年1月—2016年1月收治的79例寻常性银屑病患者,随机分为观察组和对照组,对照组常规利用卡泊三醇软膏治疗,观察组外用钙泊三醇倍他米松软膏治疗,对比两组患者的治疗效果。结果疗程结束后,观察组患者总有效率为87.5%,显著高于对照组的69.2%,差异有统计学意义(P<0.05)。观察组不良反应发生率为5.0%,低于对照组的28.2%,差异有统计学意义(P<0.01)。疗程中点观察组PASI评分为(7.5±1.0)分、疗程结束时观察组PASI评分为(1.2±0.7)分,显著低于对照组,差异有统计学意义(P<0.05)。结论寻常性银屑病患者外用钙泊三醇倍他米松软膏治疗,疗效显著,不良反应少,值得推广使用。

Objective To observe and analyze the clinical effect of calcipotriol betamethasone ointment for external use in treatment of psoriasis vulgaris. Methods Convenient selection 79 cases of patients with psoriasis vulgaris admitted and treated in our hospital from January 2015 to January 2016 were randomly divided into two groups, the control group adopted the routine calcipotriol ointment for treatment, while the observation group adopted the calcipotriol Betamethasone Ointment for external use, and the treatment effect of the two groups was compared. Results At the end of the treatment course, the total effective rate in the observation group was obviously higher than that in the control group（87.5% vs 69.2%）, and the difference had statistical significance（P0.05）, and the incidence rate of adverse reactions in the observation group was lower than that in the control group（5.0% vs 28.2%）, and the difference had statistical significance（P0.01）, and the PASI score in the middle point in the treatment course and at the end of the treatment course in the observation group was respectively（7.5±1.0） scores and（1.2±0.7）scores, which were lower than those in the control group, and the differences had statistical significance（P0.05）. Conclusion The curative effect of the calcipotriol betamethasone ointment for external use in treatment of psoriasis vulgaris is obvious, and the adverse reactions are fewer, which is worth promotion and application.