盐酸利托君在治疗先兆早产中的疗效及并发症

Curative Effect and Complications of Ritodrine Hydrochloride in Treatment of Threatened Premature Labor

目的探析盐酸利托君在治疗先兆早产中的疗效及并发症发生率。方法方便选取该院于2016年1—5月妇产科收治的54例先兆早产患者,随机分为对照组和观察组,各27例。两组均给予常规治疗,在此基础上,对照组给予硫酸镁治疗,观察组给予盐酸利托君治疗,对比分析临床治疗效果及并发症发生率。结果从疗效上看,观察组的临床治疗有效率(96.30%)明显优于对照组(70.37%);观察组的显效时间、治疗时间、住院时间以及延长妊娠时间分别为(15.31±3.98)h、(4.31±1.36)d、(6.41±2.23)d、(21.25±1.85)d均明显优于对照组的(23.14±4.23)h、(7.78±2.23)d、(10.72±4.14)d、(13.47±2.89)d,组间对比差异有统计学意义(P<0.05)。观察组的并发症发生率为7.41%,低于对照组(29.63%)(P<0.05)。结论盐酸利托君治疗先兆早产的临床效果较好,且用药安全性相对较高,可缩短住院时间,减轻经济压力和心理负担,改善患者的生活质量,具有临床推广价值。

Objective To study the curative effect and incidence rate of complications of ritodrine hydrochloride in treatment of Threatened premature labor. Methods Convenient selection 54 cases of patients with Threatened premature labor admitted and treated in the department of gynaecology and obstetrics in our hospital from January 2016 and May 2016 were randomly divided into two groups with 27 cases in each, both groups adopted the routine treatment, and the control group adopted the magnesium sulphuricum for treatment, while the observation group adopted the ritodrine hydrochloride for treatment, and the clinical treatment effect and incidence rate of complications were compared and analyzed. Results The clinical treatment effective rate in the observation group（96.30%） was obviously better than that in the control group（96.30%）,and the excellence time, treatment time, length of stay and pregnant extension time in the observation group were obviously better than those in the control group,（15.31 ±3.98）h,（4.31±1.36）d,（6.41±2.23）d,（21.25 ±1.85）d vs（23.14 ±4.23）h,（7.78 ±2.23）d,（10.72±4.14）d,（13.47±2.89）d, and the differences between groups had statistical significance（P0.05）, and the incidence rate of complications in the observation group was lower than that in the control group（7.41% vs 29.63%）（P0.05）.Conclusion The clinical effect of ritodrine hydrochloride in treatment of threatened premature labor is good, and the medication safety is relatively high, which can shorten the length of stay, relieve the economic pressure and mental burden and improve the quality of life of patients, and it is worth clinical promotion.