乳酸杆菌在儿童龋病中作用的研究进展

Progression of the function of Lactobacillus in the children dental caries

乳酸杆菌(LB)是一种产酸、耐酸性细菌,能高效代谢糖类产酸,使牙体组织脱矿,LB是龋病的主要致病菌,在龋病的发病中起到至关重要的作用,与龋病的发展密切相关,而儿童龋病又有其特点。本文对国内外儿童(年龄<12岁)龋病的流行病学、龋病的菌群分布、致病LB基因型及其与其他致病菌的相互作用在龋病发病中的作用等方面的研究进展作一综述。

Lactobacillus（LB）,which is a kind of acidproof and acid-producing bacteria,can be efficiently involved into the metabolism of sugar,contributing to the demineralization of tooth tissue. As the main cariogenic bacteria,LB plays a crucial role in the beginning phase of dental caries,and is closely associated with the development of caries. Children dental caries has its own characteristics. In this paper,we would make a review of the epidemiology of children caries（age 〈12 year old）,flora distribution and genotype of the cariogenic lactobacillus,and the interaction with other cariogenic bacteria in progress of dental caries.