无创呼吸机辅助治疗慢性阻塞性肺疾病的疗效观察

Curative effect observation of noninvasive ventilation in adjunctive therapy of chronic obstructive pulmonary disease

目的探讨无创呼吸机辅助治疗慢性阻塞性肺疾病的疗效。方法选取50例COPD合并Ⅱ型呼吸衰竭患者,其中20例采用常规治疗为对照组(A组),30例应用无创呼吸机治疗为实验组(B组);检测两组患者治疗前及治疗72h后动脉血气指标、PH值、呼吸频率、心率的指标。结果两组患者治疗后72h后的Pa O2、Pa CO2和p H值等动脉血气指标以及心率和呼吸频率均较治疗前改善(P<0.05);然而,使用呼吸机后,B组患者的Pa O2、Pa CO2、p H值以及心率和呼吸频率较A组改善更为明显(P<0.05)。结论无创呼吸机治疗慢性阻塞性肺疾病的患者临床疗效好。

Objective To explore the curative effect of noninvasive ventilation in adjunctive therapy of chronic obstructive pulmonary disease. Methods 50 cases of COPD patients with type II respiratory failure were sected as the study objects. 20 cases of them were divided into control group（group A） and treated with routine therapy, and 30 cases of them were divided into experimental group（group B） and treated with noninvasive ventilation. Indexes of arterial blood gas, pH value, respiratory rate and heart rate before and after 72 hours of the two groups were detected. Results PaO2, PaCO2 and pH values of arterial blood gas index, heart rate and respiratory rate of the two gorups were improved, compared with before treatment（P〈0.05）. However, after using the respirator, the PaO2, PaCO2, pH values, heart rate and respiratory rate of patients in group B were better than those in group A（P〈0.05）. Conclusion Noninvasive ventilation in adjunctive therapy of chronic obstructive pulmonary disease has good clinical effect.