心房颤动患者左心房大小与缺血性脑卒中相关性分析

Correlation analysis of left atrial size and cerebral arterial thrombosis of patients with atrial fibrillation

目的探讨心房颤动（atrial fibrillation,AF）患者左心房（left atrium,LA）大小与缺血性脑卒中的相关性。方法选取2015年6月-2016年10月在我院住院治疗的118例心房颤动患者,按有无缺血性脑卒中分成两组：A组（单纯房颤组）：有房颤无缺血性脑卒中;B组（卒中组）：有房颤合并缺血性脑卒中。记录患者年龄、性别、合并疾病、超声心动图指标等,一般资料进行单因素分析,多因素Logistic回归分析心房颤动发生缺血性脑卒中的危险因素。结果 A组与B组比较,两组左心房大小存在显著差异（P〈0.05）,B组LA水平明显高于A组。左心房大小、高血压病史、糖尿病病史为缺血性脑卒中的独立危险因素。结论左心房增大是导致缺血性脑卒中的高危因素,临床上应给予积极干预,预防恶性事件的发生。

Objective To explore the correlation of left atrial size and cerebral arterial thrombosis of patients with atrial fibrillation. Methods 118 patients with atrial fibrillation hospitalized in our hospital from June 2015 to October 2016 were selected and divided into group A（simple atrial fibrillation group,that was with atrial fibrillation without ischemic stroke） and group B（Stroke group,that was with atrial fibrillation combined with ischemic stroke）according to ischemic stroke or not.Age,gender,comorbidity,echocardiographic parameters,etc.of the patients were recorded.General data were carried on single factor analysis,and risk factors for ischemic stroke in atrial fibrillation was analyzed by multivariate Logistic regression analysis. Results Compared between group A and group B,there was significant difference in left atrial size between the two groups（P 〈 0.05）.The level of LA in B group was significantly higher than that in group A.Left atrial size,history of hypertension and diabetes mellitus were independent risk factors for ischemic stroke. Conclusion Left atrial enlargement is a high risk factor for ischemic stroke.Clinical intervention should be given to prevent malignant events.