体力活动水平与血脂及心血管炎症因子的相关性分析——基于不同体力活动水平女性血脂及心血管炎症因子指标数据

The Related Research of Physical Activity Level and Blood Lipid and Cardiovascular Inflammation Factors——Based on Blood Lipid and Cardiovascular Inflammation Factor Index Data of Women at Different Physical Activity Level

探讨不同体力活动水平对40-59岁女性血脂及心血管炎症因子C-反应蛋白、白介素-6、肿瘤坏死因子、载脂蛋白B的影响,旨在明确体力活动水平与血脂及血管炎症因子之间的关系。方法：以65名40-59岁女性为研究对象,采用国际体力活动量表测量其体力活动,并根据体力活动水平分为三组。分析不同体力活动水平女性血脂四项和超敏C-反应蛋白、白介素-6、肿瘤坏死因子、载脂蛋白B等血管炎症因子情况。结果：低体力活动人群甘油三脂（TG）、低密度脂蛋白（LDL）、总胆固醇（CHO）均高于中体力活动人群,高密度脂蛋白（HDL）低于中等体力活动组;低体力活动人群超敏C反应蛋白、肿瘤坏死因子浓度明显高于高体力活动人群,且差异显著（P〈0.05）;低体力活动人群的载脂蛋白B、白细胞介素-6浓度低于中体力活动人群,且差异显著（P〈0.05）;体力活动量与低密度脂蛋白呈低度负相关,体力活动量与超敏C-反应蛋白也呈低度负相关。结论：高体力活动量人群的血脂情况好于低体力活动量人群;中体力活动量人群载脂蛋白B和白细胞介素-6指标优于低、高体力活动量人群;高体力活动量人群的超敏C-反应蛋白和肿瘤坏死因子指标优于低、中体力活动量人群;体力活动量与低密度脂蛋白、超敏C-反应蛋白关系密切。

To explore the physical activity level of women 40 - 59 years blood lipids and vascular inflammatory cytokines C-reactive protein,interleukin-6,tumor necrosis factor,apolipoprotein B,and for the relationship between the physical activity,the blood lipid and vascular inflammation factors are ensured. Methods： 65 women at the age of 40 - 59 years as ordinary objects,according to the physical activity level employing international physical activity questionnaire survey,are divided into three groups. The lipids and C-four-reactive protein,interleukin-6,tumor necrosis factor,apolipoprotein B and other vascular inflammatory factors of different physical activity were analysed. Results： low physical activity group,blood lipid triglycerides（ TG）,low density lipoprotein（ LDL）,total cholesterol（ CHO） were higher than moderate level of physical activity group,high-density lipoprotein（ HDL） less than the moderate physical activity group; insufficient activity in human serum C-reactive protein. Tumor necrosis factor were significantly higher than high physical activity group,and the difference was significant（ P〈0. 05）; and lack of physical activity in human serum concentrations of interleukin-6,Apolipoprotein B below crowd moderate physical activity and the difference was significantly（ P〈0. 05）; Physical activity levels are negatively correlated with low density lipoprotein,physical activity and hypersensitive c-reactive protein are negatively correlated also. Conclusion： Lipid of high physical activity level population fared better than low physical activity; Apolipoprotein B and interleukin 6 indicators of medium physical activity in people is better than that of low and high physical activity level,hypersensitive c-reactive protein and tumor necrosis factor index high physical activity of human is better than that of low and medium physical activity; Physical activity and low density lipoprotein cholesterol（ hdl-c）,hypersensitive c- reactive protein has a close relationship.