bZIP转录因子调控植物次生代谢产物生物合成的研究进展

Regulation of secondary metabolite biosynthesis by bZPI transcription factors in plants

植物次生代谢产物是通过次生代谢产生的一类小分子有机化合物,是植物适应环境的表现,次生代谢产物也是重要药物和化工原料的来源。bZIP转录因子是普遍存在于真核生物中的一类多基因家族,可有效调控植物次生代谢产物的生物合成。本文概述了植物bZIP转录因子的结构和类型,重点阐述了bZIP转录因子调控萜类、黄酮类和生物碱等植物次生代谢产物生物合成的研究进展,并对研究前景进行了展望。深入探讨bZIP转录因子的调控机制,有助于利用基因工程技术优化植物次生代谢途径,提高次生代谢产物的含量,在新药创制、工农业生产等方面具有广泛的应用前景。

Secondary metabolites derived from secondary metabolic pathways in plants play an important role in the adaptation of plants to the ecological environment, and represent a valuable source of natural medicines and industrial chemicals, bZIP transcription factors （TFs） belong to a large gene family and generally exist in eukaryotes. This review summarizes the structure and classification of bZIP TFs, with an emphasis on research progress, methods and the biosynthetic regulation of secondary metabolites, such as terpenoids, flavonoids and alkaloids. Future prospects are also discussed. Further research on the mechanisms of bZIP TFs will increase secondary metabolite production by genetic modification of biosynthetic pathways, with wider application prospects in medicine and industrial and agricultural production.