经皮椎体后凸成形术在治疗老年骨质疏松性椎体压缩性骨折中骨水泥注射量与疗效的相关性研究

Study on the correlation of bone cement injection with and curative effect in elderly patients with osteoporotic vertebral compression fractures treated by PKP

目的研究经皮椎体后凸成形(PKP)术在治疗老年骨质疏松性椎体压缩性骨折中骨水泥注射量与疗效的相关性。方法选取2012年6月至2016年6月在我院治疗的患者200例。对患者进行回顾性分析。记录患者的性别、年龄、骨水泥注射量、术后恢复率等情况。采用双变量相关分析、线性回归等方法对上述变量进行分析。结果骨水泥的注射量和治疗疗效没有显著相关性。病椎水平和PKP术前病椎压缩率是影响骨水泥注射量的重要因素;患者的病程和术前病椎压缩率是影响患者术后疼痛视觉模拟评分法(VAS)改善率的重要因素。结论 PKP术中骨水泥注射量与治疗疗效无明显关系,不能反映治疗疗效。因此骨水泥注射量应适当,以减少并发症的发生。

Objective To investigate the correlation of percutaneous kyphoplasty（PKP） in the treatment of osteoporotic vertebral compression fractures in elderly patients. Methods Two hundred patients were randomly selected from June 2012 to June 2016 in our hospital. The patients were retrospectively analyzed. The patients＇ gender, age, bone cement injection volume and postoperative recovery rate were recorded. Bivariate correlation a- nalysis, linear regression and other methods were used to analyze the above variables. Results There was no sig- nificant association between the amount of bone cement injection and the therapeutic effect. The degree of verte- bral fracture and the rate of vertebral compression before PKP were important factors influencing the volume of bone cement injection. The course of disease and the rate of vertebral compression before operation were the important factors influencing the improvement rate of postoperative VAS. Conclusion There is no significant correlation between the injection volume of PKP and the curative effect, but it cannot reflect the curative effect of PKP （percutaneous kyphoplasty）. Therefore, the amount of bone cement injection should be appropriate to reduce the incidence of complications.