针刺联合穴位注射治疗中风后顽固性呃逆临床观察

Clinical observation of acupuncture combined with acupoint injection in the treatment of post -stroke intractable hiccup

目的：观察针刺联合穴位注射治疗中风后顽固性呃逆的临床疗效。方法采用随机对照试验方法，将120例中风后顽固性呃逆患者按照随机数字表法分为治疗组和对照组各60例，对照组患者口服巴氯芬片联合盐酸甲氧氯普胺注射液肌注，治疗组患者给予针刺联合穴位注射治疗，疗程均为1周。比较2组患者治疗前后在呃逆症状评分、总有效率、不良反应等方面的变化。结果治疗前治疗组和对照组患者呃逆症状评分分别为（5．32±1．17）和（5．25±0．65），差异无统计学意义（t ＝1．79，P ＝0．96）；治疗1 d 后治疗组和对照组患者呃逆症状评分分别为（3．97±1．24）和（3．85±1.02），差异无统计学意义（t ＝1．93，P ＝0．48）；治疗3 d 后治疗组和对照组患者呃逆症状评分分别为（2．80±0．73）和（3．75±1．11），差异有统计学意义（t ＝2.66，P ＝0．00），治疗组评分低于对照组；治疗5 d 后治疗组和对照组患者呃逆症状评分分别为（2．25±1．07）和（3．43±0．81），差异有统计学意义（t ＝2.85，P ＝0．00），治疗组评分低于对照组；治疗7 d 后治疗组和对照组患者呃逆症状评分分别为（1．27±0．66）和（2．02±0．98），差异有统计学意义（t ＝1.07，P ＝0．00），治疗组评分低于对照组；治疗组和对照组总有效率分别为90％（54／60）和65％（39／60），差异有统计学意义（χ2＝10．75，P ＝0．00），治疗组总有效率高于对照组；治疗组和对照组不良反应发生率分别为1．7％（1／60）和6．7％（4／60），差异无统计学意义（χ2＝0．84，P ＝0．36）。结论针刺联合穴位注射能够显著降低中风后顽固性呃逆，提高总有效率。

Objective To observe the clinical therapeutic effect of acupuncture combined with acupoint injection in the treatment of post -stroke intractable hiccup.Methods 120 patients with post -stroke intractable hiccup were randomly divided into treatment group（60 cases）and control groups（60 cases）according to the digital table.The patients in the control group were treated with baclofen tablets and methloxetamine hydrochloride injection, and the patients in the treatment group were treated with acupuncture combined with acupoint injection therapy.The treating period was 1 week.The scores of hiccup symptoms,the total effective rate and side effect were recorded before and after the treatment in all patients.Results The scores of hiccup symptoms before treatment in the treatment group and the control group were （5.32 ±1.17）points and （5.25 ±0.65）points respectively,there was no statistically significant difference between the two groups（t =1.79,P =0.96）.The scores of hiccup symptoms on the 1 day after treatment in the treatment group and the control group were （3.97 ±1.24）points and （3.85 ±1.02 ）points respectively,there was no statistically significant difference between the two groups（t =1.93,P =0.48）.The scores of hiccup symptoms on the 3 days after treatment in the treatment group and the control group were （2.80 ±0.73）points and （3.75 ±1.11）points respectively,there was significant difference between the two groups（t =2.66,P =0.00）, that in the treatment group was lower than the control group.The scores of hiccup symptoms on the 5 days after treatment in the treatment group and the control group were （2.25 ±1.07）points and （3.43 ±0.81）points respec-tively,there was significant difference between the two groups（t =2.85,P =0.00）,that in the treatment group was lower than the control group.The scores of hiccup symptoms on the 7 days after treatment in the treatment group and the control group were （1.27 ±0.66）points and （2.02 ±0.98）points respectively,there was significant difference＆nbsp;between the two groups（t =1.07,P =0.00）,that in the treatment group was lower than the control group.The total effective rates in the treatment group and the control group were 90%（54 /60）and 65%（39 /60）respectively,there was significant difference between the two groups（χ2 =10.75,P =0.00）.The incidence rates of side effects in the treatment group and the control group were 1.7%（1 /60）and 6.7%（4 /60）respectively,there was no statistically significant difference between the two groups（χ2 =0.84,P =0.36）.Conclusion Acupuncture combined with acu-point injection can significantly reduce the hiccup symptom score of post -stroke intractable hiccup patients on the 3, 5 and 7 days after treatment,and improve the total effective rate.