企业退休人员非酒精性脂肪性肝病合并高血压的危险因素分析

Analysis on risk factors of nonalcoholic fatty liver disease complicated with hypertension in the enterprise retirees

目的：探讨企业退休人员非酒精性脂肪肝（NAFLD）患者合并高血压的危险因素。方法收集209例经 B 超结合问卷调查诊断为 NAFLD 的企业退休人员，结合体检结果及既往史，将 NAFLD 合并高血压患者100例作为观察组，NAFLD 未合并高血压患者109例作为对照组，回顾性分析两组患者的相关资料，从中分析 NAFLD 合并高血压疾病的危险因素。结果观察组中，年龄（t ＝1．69，P ＜0．05）、体质量指数（BMI）（t ＝0．36，P ＜0．05）、腰围（t ＝0．64，P ＜0．05）、总胆固醇（TC）（t ＝2．31，P ＜0．05）、总胆红素（TBS）（t ＝6．83， P ＜0．05）、血肌酐（Scr）（t ＝2．20，P ＜0．05）均高于对照组，差异有统计学意义（P ＜0.05），Logistic 回归分析显示：TC（OR ＝4．2）是 NAFLD 合并高血压的独立影响因素。结论NAFLD 与高血压关系密切，可将 NAFLD与高血压等一起纳入慢病管理体系以提高老年人对此病的重视，有利于对 NAFLD 的进一步研究和其他慢病的管理。

Objective To observe and explore the risk factors of nonalcoholic fatty liver diseas（NAFLD） complicated with hypertension in the enterprise retirees .Methods A total of 209 NAFLD patients diagnosed by＆nbsp;ultrasound combined with questionnaire were collected in the enterprise retirees,and they were divided into the NAFLD with hypertension group（100 cases）and NAFLD without hypertension group （109 cases）after combined with physical examination results and past medical history.The relevant data of the two groups were retrospectively analyzed,and the risk factors of NAFLD complicated with hypertension disease were analyzed.Results The levels of age（t =1.69,P 〈0.05）,body mass index（BMI）（t =0.36,P 〈0.05）,waist circumference（t =0.64,P 〈0.05）, total cholesterol（TC）（t =2.31,P 〈0.05）,total bilirubin（TBS）（t =6.83,P 〈0.05）,serum creatinine（Scr）（t =2. 20,P 〈0.05）in NAFLD complicated with hypertension group were higher than those in NAFLD group,and the differ-ences were statistically significant（P 〈0.01 or P 〈0.05）.The logistic regression analysis showed that TC（OR =4.2）was the independent influencing factor of NAFLD with hypertension.Conclusion NAFLD is closely associated with hypertension,NAFLD can be incorporated into chronic disease management system with high blood pressure in order to improve the value of the disease in the elderly,and it is conducive to the further study of NAFLD and the management of other chronic disease.