针刺对颈动脉支架术后炎性因子及预后的影响

Effect of Acupuncture Treatment on Inflammatory Factors and Prognosis in Patients with Carotid Artery Stenting

目的 :探讨穴位针刺对颈动脉支架术(CAS)后炎性因子及预后的影响。方法 :观察66例颈动脉支架术后患者,按随机数字表法分为对照组和针刺组各33例,对照组采用常规药物治疗,针刺组在对照组的基础上联合使用针刺治疗,分别观察治疗前后两组C反应蛋白(CRP)、血浆白细胞介素-6(IL-6)水平变化及预后。结果:两组术后1 h、术后10 d CRP、IL-6水平显著高于术前,手术前后比较差异有统计学意义(P<0.05),针刺组术后10 d、6个月CRP、IL-6水平、脑血管事件发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:针刺可降低颈动脉支架术后CRP、IL-6水平,减少脑血管事件的发生。

Objective：To study the effect of acupuncture on inflammatory factors and prognosis in patients with carotid artery stenting（CAS）. Methods：Sixty-six patients with CAS were randomly divided into control group and acupuncture group,33 cases in each group. The control group was given routine drug treatment,while the acupuncture group was given acupuncture and routine drug treatment. C reactive protein（CRP）,plasma interleukin-6（IL-6） level and cerebrovascular events were observed before and after CAS. Results ：CRP,the IL-6 level at 1 hr and 10 days after CAS were significantly higher than those before CAS in two groups. CRP,IL-6 and incidence of cerebrovascular events in the acupuncture group at 10 days and 6months after CAS were significantly lower than those in the control group,with statistical signifance（P〈0.05）.Conclusion：Acupuncture could reduce the level of CRP and IL-6 after CAS and the incidence of cerebrovascular events in the patients with CAS.