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临床药师参与肥厚型梗阻性心肌病伴高血压患者治疗方案一例

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摘要 肥厚型心肌病是以心肌非对称向心性肥厚、左心室舒张期充盈受限、室壁顺应性下降为特征的一种常染色体显性遗传性疾病,发病比例为1/500[1-2]。其中,约25%的肥厚型心肌病患者存在左室流出道梗阻,称为肥厚型梗阻性心肌病[3]。血管紧张素转化酶抑制剂(ACEI)为临床一线抗高血压药物,通过扩张动脉,降低后负荷,起到降低血压的作用,但同时可能增加左室流出道压差,加重其梗阻程度,肥厚型梗阻性心肌病患者应予以警惕。本文就1例肥厚型梗阻性心肌病伴高血压患者停用 ACEI 的病例进行分析,以期为临床用药提供参考。
出处 《中国实用医刊》 2017年第4期124-125,共2页 Chinese Journal of Practical Medicine
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