腹腔镜联合药物治疗子宫内膜异位症的疗效及对患者生育功能的影响

Efficacy of laparoscopy combined with drug therapy on endometriosis and its effect on the fertility of patients

目的：分析研究腹腔镜联合药物治疗子宫内膜异位症的治疗效果及对患者生育功能的影响。方法选取2013年3月至2015年1月68例子宫内膜异位症患者作为研究对象，随机分为联合用药组与单一手术组。单一手术组采用腹腔镜手术治疗，联合用药组在单一手术组手术治疗基础上服用孕三烯酮，对比观察两组患者治疗效果、月经及排卵恢复时间和术后1年妊娠成功率。结果联合用药组治疗总有效率为91.18％，单一手术组为85.29％，组间比较差异未见统计学意义（P ＞0.05）；联合用药组月经及排卵恢复时间均明显少于单一手术组，差异有统计学意义（P ＜0.05）；联合用药组术后1年妊娠成功率为26.47％（9/34），单一手术组为5.88％（2/34），组间比较差异有统计学意义（P ＜0.05）。结论联合腹腔镜手术及药物治疗子宫内膜异位症患者效果显著，可有效缩短患者月经及排卵恢复时间，提高其妊娠成功率，具有一定临床价值，值得推广运用。

Objective To study the effect of laparoscopy combined with drug therapy on endometriosis and its effect on the fertility of the patients. Methods Sixty-eight cases of endometriosis from March 2013 to January 2015 were randomly divided into the combined treatment group and the single operation group. The single operation group was treated by laparoscopic operation,and the combination therapy group was given gestrinone of the pregnant women on the basis of the single operation group. The effect of menstruation and ovulation recovery time and postoperative 1 year pregnancy success rate between the two groups were compared. Results The total effective rate in combined treatment group was 91. 18% ,and that in the single operation group was 85. 29% ,there was no significant difference between the two groups（P 〉 0. 05）. The recovery time of menstruation and ovulation were significantly less than those of single operation group,and the differences were significant（P 〈 0. 05）. The success rate of pregnancy after 1 year of combined treatment group was 26. 47%（9/ 34）,that of the single operation group was 5. 88%（2/ 34）,the difference was significant（ P 〈 0. 05）. Conclusions Laparoscopic combined with drug in treatment of endometriosis patients has significant effect,it can effectively shorten the recovery time of menstruation and ovulation,increase the success rate of pregnancy,has a certain clinical value,it is worth promoting.