摘要
胰腺神经内分泌肿瘤(pNEN)是一类高度异质的少见肿瘤,对于局部可切除的肿瘤,手术是惟一的根治性治疗方式;而对于确诊时已有局部进展或远处转移的患者,内科治疗是主要的治疗方式。内科治疗包括生物治疗、靶向治疗和化学治疗。在内科治疗药物的选择上需综合考虑肿瘤功能状态、生长抑素受体表达情况、病理分级、肿瘤分期和药物毒性谱。
Pancreatic neuroendocrine neoplasm （pNEN） is a kind of rare neoplasms with high heterogeneity. Surgery is the first choice to cure local reseetable tumor. However, for patients with local advanced tumor or distant metastasis, medical treatment is the main option. Medical treatment mainly encompasses biotherapy, targeted therapy and chemotherapy. Clinicians should make therapeutic option for patients based on the functional status and somatostatin receptor status of the tumor, tumor grade, tumor stage and drug toxicity profile.
出处
《胃肠病学》
2017年第2期65-69,共5页
Chinese Journal of Gastroenterology
关键词
胰腺
神经内分泌瘤
生物治疗
分子靶向治疗
化学治疗
Pancreas
Neuroendoerine Tumors
Biotherapy
Molecular Targeted Therapy
Chemotherapy
