2型糖尿病多种危险因素强化治疗对患者发生心血管意外事件的影响

The Influence Multiple risk Factors in Patients with Type 2 Diabeteson Cardiovascular Accidents of Intensive Treatment

目的分析2型糖尿病患者进行多种危险因素强化治疗对发生心血管意外事件的影响。方法选取我院2011年1月—2015年12月诊治的2型糖尿病患者164例,根据住院先后顺序分为两组,对照组80例采用综合治疗,包括常规降糖治疗、危险因素药物治疗、健康教育干预、饮食控制和运动保健干预,观察组84例在综合治疗的基础上,增加心理指导及随访干预,比较各组患者血糖控制情况、生活质量及心血管意外事件的发生情况。结果观察组干预后空腹血糖(5.4±0.2)mmol/L,显著低于对照组(6.8±0.3)mmol/L,2 h餐后血糖(9.8±0.5)mmol/L显著低于对照组(10.6±0.6)mmol/L,HbA1c(5.2±0.2)%也显著低于对照组(6.4±0.4)%,差异均具有统计学意义(P<0.05);观察组心血管意外事件发生率为7.1%(3/42),低于对照组的20.0%(8/40),但差异无统计学意义(P>0.05)。结论 2型糖尿病患者在常规降糖治疗、多种危险因素强化治疗的基础上进行心理指导和随访能有效降低血糖,提高生活质量,有降低心血管意外事件发生风险的趋势。

OBJECTIVE To analyze the effect on cardiovascular accidents of intensive treatment to a variety of risk factors in patients with type 2 diabetes.METHODS Trom January 2011 and December 2015,it admitted 164 patients with type 2 diabetes,according to admission order divided into two groups,conventional treatment group（control group）and 80 patients with routine hypoglycemic therapy,intensive treatment group（hereinafter referred to as observation group）84 cases on the basis of routine hypoglycemic treatment,strengthened treatment（including risk factors for drug therapy,health education intervention,diet control,exercise care and psychological guidance）,to comporre the blood glucose control the quality of life,and cardiovascular accident happening betwee these two groups.RESULTS After the intervention in the observation group fasting glucose（5.4±0.2）mmol/L was significantly lower than control group（6.8±0.3）mmol/L,2 h postprandial blood glucose（9.8±0.5）mmol/L was significantly lower than control group（10.6±0.6）mmol/L,HbA1c（5.2±0.2）%was also significantly lower than control group（6.4±0.4）%,differences were statistically significant（P0.05）;the incidence of cardiovascular accidents in the observation group was 7.1%（3/42）,which was lower than control group（20.0%,8/40）,although the difference were not statistically significant（P0.05）.CONCLUSION In patients with type 2 diabetes,based on the conventional hypoglycemic and the therapy of multiple risk factors,the psychological guidance and follow-up should reduce blood sugar,improve the quality of life and may reduce cardiovascular accident risk.