摘要
目的探讨托拉塞米联合卡托普利治疗慢性舒张性心力衰竭患者的临床疗效。方法选取2014年10月至2015年10月沈阳市经济开发区人民医院心血管内科收治的76例慢性舒张性心力衰竭患者作为研究对象,按随机数字表法分为试验组和对照组,各38例。对照组患者予以托拉塞米,试验组患者在对照组基础上予以卡托普利,比较两组患者临床疗效、脑钠肽(BNP)水平以及6 min步行距离。结果试验组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);治疗后,试验组患者BNP水平显著低于对照组,6 min步行距离明显高于对照组,差异均有统计学意义(均P<0.05)。结论托拉塞米联合卡托普利治疗慢性舒张性心力衰竭临床疗效显著,能够有效改善心功能。
Objective To investigate the clinical curative effect of torasemide combined with Kato Pury in the treatment of patients with chronic diastolic heart failure.Methods From October 2014 to October 2015,76 patients with chronic diastolic heart failure were randomly divided into experimental group and control group,each of 38 patients with chronic diastolic heart failure were randomly divided into experimental group and control group,each of cases. The control group was treated with torasemide,experimental group patients in the control group treated with captopril, compared two groups of patients with clinical curative effect,brain natriuretic peptide(BNP) level and 6 min walking distance.Results Treatment of the total effective rate in experimental group was significantly higher than the control group,the difference was statistically significant(P〈0.05);after treatment,patients in the experimental group BNP level was significantly lower than the control group of 6 min walking distance was significantly higher than the control group,the differences were statistically significant(P 〈0.05).Conclusion Kato Pury was treated with torasemide combined with chronic diastolic heart failure clinical curative effect,can effectively improve heart function.
出处
《中国药物经济学》
2017年第2期49-51,共3页
China Journal of Pharmaceutical Economics