肠道非霍奇金淋巴瘤46例的临床及病理诊断特点分析

Clinical and Pathological Features of 46 Cases of Intestinal Non-Hodgkin Lymphoma

目的探讨肠道非霍奇金淋巴瘤(NHL)的临床及病理诊断特点。方法回顾性分析病理确诊的46例肠道NHL患者的病例资料。结果全组患者中小肠及大肠部位来源的NHL分别为26例及20例。肠病相关性T细胞淋巴瘤在大肠部位的发病率较小肠部位高,差异有统计学意义(P=0.0347)。老年(≥60岁)患者的肠道NHL恶性程度远较年龄<60岁的患者为低,差异有统计学意义(P=0.0116)。结论肠病相关性T细胞淋巴瘤在大肠部位的发病率较高;且年龄<60岁患者的肠道NHL恶性程度较高,值得临床重视。

Objective To investigate the clinical and pathological features of intestinal non Hodgkin lymphoma（ NHL）.Methods The case data of 46 patients with intestinal NHL diagnosed by pathology were retrospectively analyzed. Results The small intestine NHL and the large intestine NHL in the whole group were 26 cases and 20 cases respectively.The morbidity of enteropathy associated T cell lymphoma incidence in parts of the large intestine is higher than that of small intestine parts,the difference was statistically significant（ P = 0. 0347）.The malignancy grade of intestinal NHL in elderly patients（ ≥60） is lower than patients under 60,the difference was statistically significant（ P = 0. 0116）. Conclusion The morbidity of enteropathy associated T cell lymphoma in parts of large intestines is higher,and the malignancy grade is lower in patients under 60.The conclusion is worthy of clinical attention.