1Green A,Christian Hirsch N,Pramming SK.The changing world demography of type 2 diabetes.Diabetes Metab Res Rev,2003,19:3-7.
2Hegele RA,Cao H,Harris SB,et al.The hepatic nuclear factor-1alpha G319S variant is associated with early-onset type 2 diabetes in Canadian Oji-Cree.J Clin Endocrinol Metab,1999,84:1077-1082.
3Triggs-Raine BL,Kirkpatrick RD,Kelly SL,et al.HNF1-alpha G319S,a transactivation-deficient mutant,is associated with altered dynamics of diabetes onset in an Oji-Cree community.Proc Nat Acad Sci,2002,99:4614-4619.
4Urhammer SA,Hansen T,Ekstrom CT,et al.The Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test:evidence from studies of 231 glucose-tolerant first degree relatives of type 2 diabetic probands.J Clin Endocrinol Metab,1998,83:4506-4509.
6Ng MC,Lee SC,Ko GT,et al.Familial early-onset type 2 diabetes in Chinese patients:obesity and genetics have more significant roles than autoimmunity.Diabetes Care,2001,24:663-671.
7Vaxillaire M,Rouard M,Yamagata K,et al.Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young(MODY3).Hum Mol Genet,1997,6:583-586.
8Hansen T,Eiberg H,Rouard M,et al.Novel MODY3 mutations in the hepatocyte nuclear factor-1alpha gene:evidence for a hyperexcitability of pancreatic beta-cells to intravenous secretagogues in a glucose-tolerant carrier of a P447L mutation.Diabetes,1997,46:726-730.
