远红外线及近红外线的光生物学效应在眼病的应用研究

Application study on the far-red/near-infrared photobiomodulation in ocular disease

低能量的远红／近红外光（far-red／near—infrared，FR／NIR）通过减少细胞死亡、增强线粒体功能等光生物学效应（photobiomodulation，PBM）来促进组织伤口愈合。因其能够穿透组织到达视网膜，近年应用于眼病治疗，特别是眼底病，如甲醇中毒性视网膜病变、视网膜光损伤、遗传性视网膜病变、年龄相关性黄斑病变、糖尿病视网膜病变、早产儿视网膜病变等。PBM不会对视网膜及其他组织造成损伤，从而为眼病带来一种新型、非侵入性、安全有效的治疗方法。

The photobiomodulation （PBM） of low energy photon irradiation in the far-red （FR） to near-infrared （N/R） light can prevent cell death, enhance the function of mitochondria, accelerate wound healing. FR/NIR light can penetrate tissues and reach to the retina, so researchers applied it to the treatment of ocular disease, particularly in retinal disease, such as methanol intoxication in the retina, light-induced retinal damage, retinitis pigmentosa, age related maeular degeneration, diabetic retinopathy, retinopathy of prematurity and so on. PBM won＇ t damage retina and other tissues. It will offer a novel, non-invasive, safty and effectiveness treatment method for ocular disease.