Lp-PLA2、hs-CRP在ACS急性期的诊断价值

Diagnosis value of Lp-PLA2 and hs-CRP in acute phase of ACS

目的研究脂蛋白相关磷脂酶A2(Lp-PLA2)与超敏C反应蛋白(hs-CRP)在急性冠状动脉综合征(ACS)的诊断价值。方法选取从2014年3月~2016年3月期间,在我院检验的82例急性冠状动脉综合征患者作为观察组,并将同期的健康体检者中选取82例作为对照组,观察两组对象的脂蛋白相关磷脂酶A2和超敏C反应蛋白生活指标水平。观察组男46例、女36例,年龄31~75岁,平均(58.3±11.6)岁;对照组男44例、女38例,年龄32~74岁,平均(59.1±10.9)岁;两组性别、年龄比较差异无统计学意义,具有可比性。结果两组研究对象在脂蛋白相关磷脂酶A2(Lp-PLA2)与超敏C反应蛋白(hs-CRP)水平上,观察组要高于对照组。结论超敏C反应蛋白和脂蛋白相关磷脂酶A2在急性冠状动脉综合征的发生发展过程中起着重要的作用。

Objective To study the diagnosis value of lipoprotein-associated pbospholipase A2 （Lp-PLA2） and high sensitive C-reactive protein （（hs-CRP） in acute coronary syndrome（ACS）. Methods 82 patients with ACS cured in our hospital from March 2014 to March 2016 were selected as observation group, meanwhile 82 healthy patients over the same period were selected as control group. The index levels of lipoprotein-associated phospholipase A2 （Lp-PLA2） and high sensitive C-reactive protein （hs-CRP） of the two groups were observed. There were 46 males and 36 femals in observation group, aging from 31-75, average age （58.3 ±11.6）. There were 44 males, 38 femals in control group aging from 32-74, average age （59.1 ±10.9）. The difference of sex and age had no statistical significance between the 2 groups. It was comparable. Results The lipoprotein-associated phospholipase A2 （Lp-PLA2） and high sensitive C-reactive protein （hs-CRP） of observation group were higher than those of control group. Conclusion Llipoprotein-associated phospholipase A2 （Lp-PLA2） and high sensitive C-reactive protein （hs-CRP） play a significant role in the development of acute coronary syndrome（ACS）.