上海市2002--2006年胰腺癌人群生存状况研究

Analysis on the survival situation of pancreatic cancer patients in Shanghai from 2002 to 2006

目的分析上海2002—2006年发病的胰腺癌患者生存情况。方法利用上海市肿瘤登记处收集的2002—2006年胰腺癌登记和生存随访报告资料,采用寿命表法和EdererⅡ法计算胰腺癌患者的观察生存率(OS)和相对生存率(RS),分析影响胰腺癌患者生存率的因素。结果 2002—2006年上海市胰腺癌患者5年OS为6.63%,RS为10.11%。不同年龄段胰腺癌患者的5年OS不同,随着年龄增大,生存率逐渐降低。诊断时期为Ⅰ期、Ⅱ期的胰腺癌患者生存率高于Ⅲ期、Ⅳ期。肿瘤位于胰体的患者生存率高于其他部位。不同性别、市郊间患者生存率无明显差别。30年间,上海市区男女胰腺癌生存率均有所上升。结论上海市胰腺癌生存率逐步提高,年龄、肿瘤分期、亚部位等因素对胰腺癌生存率有影响。

Objective To analyze survival situation of pancreatic cancer patients in Shanghai from 2002 to 2006. Methods Based on the cancer registration data collected by Shanghai Cancer Registry for the pancreatic cancer patients in Shanghai from 2002 to 2006 as well as the reports of the follow-up visits thereof, the Life Table and the Ederer II method were used to calculate the observed survival （ OS） and the relative survival （ RS ） thereof and to analyze the factors influencing survival rates thereof. Results The 5-year OS and RS of pancreatic cancer patients in Shanghai from 2002 to 2006 were 6.63% and 10.11% , respectively. The 5-year OS varied with each age group of pancreatic cancer patients. With the age increase of pancreatic cancer patients, the survival rate thereof gradually decreased. The survival rates of pancreatic cancer patients diagnosed to be at Phase I and Phase II were higher than those thereof diagnosed to be at Phase III and Phase IV. The survival rate of the patients for whom pancreatic cancer was sited at body of pancreas was higher than that of the patients for whom pancreatic cancer was sited elsewhere. For the survival rate thereof, there were no significant differences between different genders, or between the urban and the suburbs/outskirts. In the past 30 years, the survival rates for both male and female patients with pancreatic cancer in the urban area of Shanghai increased to a certain extent. Conclusion The survival rate of pancreatic cancer patients in Shanghai increases on a yearly basis. Age （ of patients ） , phasing（ of pancreatic cancer ） , subsite （ location ） （ of pancreatic cancer ） , etc. will all influence the survival rates of pancreatic cancer patients.